Isolation, Characterization and Evaluation of Anti-convulsant Activity of Rubus Antidiabetic Activity of the Plant Abutilon indicum in Streptozotocin Induced. Abutilon hirtum extract and fractions exhibited anti-inflammatory analgesic, antipyretic and antipyretic activities which may be attributed by the. Abutilon indicum Sweet is an Asia phytomedicine traditionally used to treat several disorders, including diabetes mellitus. However, molecular.

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Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Diabetes or obesity causes substantial morbidity, mortality and long-term complications, and remains an important risk factor for cardiovascular disease [ 1 ]. Rajesh Garg and V. However, traditional antidiabetic plants possess less adequate scientific or medicinal data support in spite of the fact that the World Health Organization still recommends further evaluation of their accepted use [ 89 ].

Clayton, Medical Plants in Thailand bautilon, vol.

In addition, an attempt was made to identify the class of phytochemicals present in the leaves and also attribute the pharmacological property of the leaves to the particular type of phytochemicals. The resulting water fraction was freeze-dried, followed by generating brown powder Insulin resistance is a key feature in type 2 DM as well as in obesity and plays an important pathophysiological role [ 3 ].

As demonstrated in this study, extract of A. This study demonstrates that the milk decoction of AR is potent as compared to aqueous decoction of AR.


Volume2,Issue2 – Pharmacognosy Phytochemistry

The native Southeast Asian plant A. With respect to its traditional use, A. Abuilon oil is also an ingradient in many ointments, liniments and lotions for treating minor aches and pains as well as colds, when applied externally.

Pieces of diaphragms were incubated with various concentrations of the crude extract for 1. We have reported that the phytochemical analysis of the whole plant extract revealed the presence of alkaloids, flavonoids, and tannins [ 11 ].

A traditional belief regarding mode of administration of Asparagus antisiabetic AR says that Ksheerpaka milk decoction of Shatavari Asparagus racemosus is more potent as galactogogue than any other form of dosage. Mukhtar, Sayeed Ahmad Abstract.

Monthly Publishing Peer Reviewed Journal

Compound II-9, 10 epoxynonacosane have been isolated from the methanolic aerial extract of the Rubus abutilno. Evidence-Based Complementary and Alternative Medicine. Journal Issues Vol 20, Dec. Originally, TZDs were identified based on their antihyperglycemic activity, but they are also able to improve other abnormalities associated with type 2 diabetes, such as hyperlipidemia, atherosclerosis, hypertension, chronic inflammation and fibrinolytic state.

View at Google Scholar Aactivity. View at Google Scholar K. However, prior to treatment administration day 0basal plasma glucose concentration did not significantly differ between groups.

Summary of antidiabetic effects against insulin resistance of A. Since troglitazone TGZ was voluntarily withdrawn from the market in March due to occurrence antidiwbetic severe idiosyncratic liver injury, it is necessary to establish a safer compound that shows antidiabetic activity. View at Google Scholar M. For adipocyte differentiation, differentiation medium containing 0.


The leaves, twigs and roots of A.

Anti-diabetic and analgesic activity of leaves of abutilon indicum

Standardization problems arise from the complex composition of drugs which are used in the form of whole plant, parts of the plants and of plant extract. In view of this that milk decoction of AR can stimulate more milk production in lactating females, experiments were performed to determine the potentiality of zntidiabetic over aqueous decoction of AR as galactogogue in rats.

Traditionally the plant parts are used as sour, astringent and diuretic and is useful in conditions such vata, tumours, fever, neuralgia and splenopathy.

The findings of antidiabetic properties in this study are summarized in Figure antidiabsticand support the ethnobotanical use of A. The abufilon revealed that the leaves contain steroids, sapogenins, carbohydrates and flavonoids.

Indexed in Science Citation Index Expanded. These results suggest that the extract from A. Pharmacognostical Evaluation of Tylophora indica Burm.

Thus, we examined the possibility that the extract may stimulate glucose transport through a mechanism similar to insulin signaling in C2C12 myotubes and 3T3-L1 adipocytes. We found that A.